ANGPTL8: An Important Regulator in Metabolic Disorders

Metabolic Syndrome: An Important Health Issue in Iran

Metabolic syndrome (MetS) is a major metabolic disorder worldwide which is characterized by having three or more of the five metabolic abnormalities. These metabolic abnormalities include abdominal obesity (waist circumference &ge; 90 cm for men and &ge; 80 cm for women), high triglyceride levels (TG) (&le; 150 mg/dL), decreased high density lipoprotein cholesterol (HDL-c) (< 40 mg/dL in men an...

Is Gestational Diabetes Mellitus an Important Contributor to Metabolic Disorders in Trinidad and Tobago?

Objective. To investigate the incidence of Gestational Diabetes Mellitus at the Mt. Hope Women's Hospital and to describe its epidemiological pattern. Design. A retrospective observational study (Jan 2005 to Dec 2007). Setting. A teaching hospital of The University of the West Indies. Population/Sample. Pregnant women who gave birth. Methods. A sample size of 720. The variables analyzed were: a...

Hepcidin: an important iron metabolism regulator in chronic kidney disease.

Anemia is a common complication and its impact on morbimortality in patients with chronic kidney disease (CKD) is well known. The discovery of hepcidin and its functions has contributed to a better understanding of iron metabolism disorders in CKD anemia. Hepcidin is a peptide mainly produced by hepatocytes and, through a connection with ferroportin, it regulates iron absorption in the duodenum...

GLP1, an Important Regulator of Intestinal Lipid Metabolism.

S100 Proteins As an Important Regulator of Macrophage Inflammation

The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of intracellular and extracellular functions through regulating calcium balance, cell apoptosis, migration, proliferation, differentiation, energy metabolism, and inflammation. The intracellular functions of S100 proteins involve interaction with intracellular receptors, membrane protein recruitment/transporta...